Genetic Predisposition to Pcos
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چکیده
The genetic component appears to be inherited in an autosomal dominant fashion. This means that each child has a 50% chance of inheriting. The genetic variant(s) can be inherited from either the father or the mother, and can be passed along to both sons and daughters. Current understanding of the pathogenesis of the syndrome suggests, that it is a complex multigenic disorder (a genetic problem caused by more abnormalities in the genetic information DNA).
منابع مشابه
GENETIC PREDISPOSITION TO PCOS Predisposition to developing polycystic ovary syndrome (PCOS)
The genetic component appears to be inherited in an autosomal dominant fashion. This means that each child has a 50% chance of inheriting. The genetic variant(s) can be inherited from either the father or the mother, and can be passed along to both sons and daughters. Current understanding of the pathogenesis of the syndrome suggests, that it is a complex multigenic disorder (a genetic problem ...
متن کاملGENETIC PREDISPOSITION TO PCOS Predisposition to developing polycystic ovary syndrome (PCOS)
The genetic component appears to be inherited in an autosomal dominant fashion. This means that each child has a 50% chance of inheriting. The genetic variant(s) can be inherited from either the father or the mother, and can be passed along to both sons and daughters. Current understanding of the pathogenesis of the syndrome suggests, that it is a complex multigenic disorder (a genetic problem ...
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Polycystic ovary syndrome (PCOS) is a prevalent hyperandrogenic infertility and cardiometabolic disorder that increases a woman's lifetime risk of type 2 diabetes mellitus. It is heritable and intensely familial. Progress toward a cure has been delayed by absence of an etiology. Evidence is mounting, however, for in utero T excess, together with gestational hyperglycemia, contributing to either...
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Polycystic Ovarian syndrome (PCOS) is a common endocrine disorder with a global prevalence of 5-10% among women of reproductive age. PCOS is characterized by chronic anovulation, polycystic ovaries, hyperandrogenism, hirsutism, overweight, insulin resistance, and infertility. It is well-known that PCOS is a complex trait similar to type-2 diabetes in which both genetic and environmental factors...
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Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility in women. It is also associated with metabolic disturbances that place women at increased risk for obesity and type 2 diabetes. There is strong evidence for familial clustering of PCOS and a genetic predisposition. However, the gene(s) responsible for the PCOS phenotypes have not been elucidated. This two-phase fam...
متن کاملPolycystic ovaries in childhood: a common finding in daughters of PCOS patients. A pilot study.
BACKGROUND Polycystic ovarian syndrome (PCOS) is a controversial endocrine pathology and, recently, it has been suggested that the condition is hereditary. The aim of this study was to prospectively determine in daughters of patients with PCOS, by ultrasonographic (US) and colour Doppler analyses, the incidence of polycystic ovaries and search any correlation with specific hormonal parameters. ...
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تاریخ انتشار 2017